A serious three-vehicle crash has closed the M1 northbound between junction 5 and junction 6.
Two cars and a lorry have been involved in a collision at around 9.40am today.
Police and paramedics are on scene.
The lorry is on its side and a blue Toyota aygo overturned in the carriageway following the crash.
The occupants of the Toyota have been taken by ambulance to St Mary’s Hospital in London.
The lorry driver and the driver of a white Nissan Juke suffered slight injuries.
Traffic is being diverted via the A41 northbound and the A405 eastbound.
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