Saracens take on world champions South Africa in front of an expected 40,000 fans at Wembley tonight.
The Men in Black have picked a strong lineup featuring seven South Africans including skipper Wikus van Heerden and Neil de Kock.
The Springboks have made four changes from the team beaten at Leicester Tigers and will be determined to get a result after Friday's loss in France.
Sarries director of rugby Brendan Venter said: "It's going to be a fantastic occasion. To have the chance to face an international side is an honour but to face the world champions at Wembley Stadium is something very special.
"It's a great opportunity for the players in our side and there will also be a few familiar faces on either side."
In the lead up to the match, South Africa head coach Peter de Villiers accused Venter of "unethical" behaviour after watching his squad train in St Albans. This is only likely to increase the edge between the sides in this highly anticipated showdown.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here